Review

[International Immunopharmacology] The authors explore the physiological functions and regulatory mechanisms of Piezo1 and its impact on innate and adaptive immunity. This may offer new insights into diagnostics and therapeutics for the prevention and treatment of diseases and surgical infections.

[Annals of Neurology] Scientists present the state-of-the-art and future directions of the use of CAR-T in immune-mediated neurological dieases

[Archives of Dermatological Research] Congenital epidermodysplasia verruciformis is a Genodermatosis linked to different inheritance patterns and mutations of the EVER1/TMC6 and EVER2/TMC8 genes. There is an acquired form (AEV) associated with immunodeficiency states, including HIV infection; however, the literature about AEV is limited and imprecise.

[Nature Reviews Molecular Cell Biology] The authors review recent insights into the diverse cellular functions of tau and the pathology of tau inclusions and explore the potential for therapeutic interventions.

[Nature Reviews Rheumatology] Integrins are key regulators of cell–matrix interactions during joint development and joint tissue homeostasis, as well as in the development of osteoarthritis.

[Nature Immunology] Scientists outline the immunological control of systemic lupus erythematosus and looks to experimental tools and approaches that are improving our understanding of the complex contribution of interacting genetics, environment, sex and immunoregulatory factors and their interface with processes inherent to tissue parenchymal cells.