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Zika Virus: Critical Crosstalk between Pathogenesis, Cytopathic Effects, and Macroautophagy

[Journal Of Cellular Biochemistry] Scientists perform a narrative review of the molecular connection between macroautophagy and Zika virus infection while focusing on the roles of the structural and nonstructural proteins.

Reshaping of the Tumor Microenvironment by Cellular Senescence: An Opportunity for Senotherapies

[Developmental Cell] Scientists discuss the different types of senescent cells present in the tumor microenvironment (TME) and how these senescent cells and their senescence-associated secretory phenotype reshape the TME, affect immune responses, and influence cancer progression.

T Cells in Health and Disease

[Signal Transduction and Targeted Therapy] Investigators summarize the current understanding of T cell development, CD4+ and CD8+ T cell classification, and differentiation in physiological settings.

Mesenchymal Stem Cells Can Improve Discogenic Pain in Patients with Intervertebral Disc Degeneration: A Systematic Review and Meta-Analysis

[Frontiers In Bioengineering And Biotechnology] This meta-analysis indicated that mesenchymal stem cells therapy may be effective in relieving pain and improving Oswestry Disability Index significantly in patients with lumbar discogenic pain.

Cancer-Associated Fibroblasts: Mediators of Head and Neck Tumor Microenvironment Remodeling

[Biochimica Et Biophysica Acta-Reviews On Cancer] The pleiotropic effect of cancer-associated fibroblasts in the tumor microenvironment is likely to reflect the heterogeneity and plasticity of their population, with context-dependent effects on carcinogenesis.

Radiomics for Characterization of the Glioma Immune Microenvironment

[NPJ Precision Oncology] The authors provide an overview of the glioma microenvironment, describe novel approaches for clustering patients based on their tumor immune profile, and discuss the latest progress on utilization of radiomics for immune profiling of glioma based on current literature.

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