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western blot analysis

miR-125a-5p and miR-7 Inhibits the Proliferation, Migration and Invasion of Vascular Smooth Muscle Cell by Targeting EGFR

[Molecular Medicine Reports] Scientists elucidated the functions of miR‑125a‑5p and miR‑7 in vascular smooth muscle cells and investigated the associated molecular mechanisms.

BRUCE Silencing Leads to Axonal Dystrophy by Repressing Autophagosome-Lysosome Fusion in Alzheimer’s Disease

[nan] Scientists identified a microRNA that altered related components of the transport machinery to affect brain-derived neurotrophic factor retrograde signaling deficits in Alzheimer’s disease.

Corneal Lymphangiogenesis in Dry Eye Disease Is Regulated by Substance P/Neurokinin-1 Receptor System through Controlling Expression of Vascular Endothelial Growth Factor Receptor 3

[Ocular Surface] Immunocytochemistry, angiogenesis assay, and western blot analysis of human dermal lymphatic endothelial cells were conducted to assess the involvement of substance P/neurokinin-1 receptor system in lymphangiogenesis.

CHIP-Overexpressing Wharton’s Jelly-Derived Mesenchymal Stem Cells Attenuate Hyperglycemia-Induced Oxidative Stress-Mediated Kidney Injuries in Diabetic Rats

[Free Radical Biology and Medicine] Western blot analysis, flow cytometry, and MitoSOX staining revealed that hyperglycemia-induced mitochondrial oxidative stress production and apoptosis were attenuated in CHIP-overexpressing Wharton's jelly-derived mesenchymal stem cells

MicroRNA-26a Shuttled by Extracellular Vesicles Secreted from Adipose-Derived Mesenchymal Stem Cells Reduce Neuronal Damage through KLF9-Mediated Regulation of TRAF2/KLF2 Axis

[Adipocyte] Researchers investigated the role of miR-26a shuttled by extracellular vesicles derived from adipose-derived MSCs in neuronal damage.

VALD-3, a Schiff Base Ligand Synthesized from O-Vanillin Derivatives, Induces Cell Cycle Arrest and Apoptosis in Breast Cancer Cells by Inhibiting the Wnt/β-Catenin Pathway

[Scientific Reports] Scientists investigated the cytotoxic and apoptotic effects of VALD-3, a Schiff base ligand synthesized from o-vanillin derivatives, on human breast cancer cells and the possible underlying mechanisms.

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