Corneal Lymphangiogenesis in Dry Eye Disease Is Regulated by Substance P/Neurokinin-1 Receptor System through Controlling Expression of Vascular Endothelial Growth Factor Receptor 3

Immunocytochemistry, angiogenesis assay, and western blot analysis of human dermal lymphatic endothelial cells were conducted to assess the involvement of substance P/neurokinin-1 receptor system in lymphangiogenesis.