Tag results:

western blot analysis

Ailanthone Suppresses the Activity of Human Colorectal Cancer Cells through the STAT3 Signaling Pathway

[International Journal of Molecular Medicine] The authors investigated the antitumor effects of Ailanthone on HCT116 and SW620 colon cancer cells, and to analyze the underlying molecular mechanisms.

Adiponectin Triggers Breast Cancer Cell Death via Fatty Acid Metabolic Reprogramming

[Journal of Experimental & Clinical Cancer Research] The authors elucidated the multifaceted role of adiponectin in tumor fatty acid metabolic reprogramming and provided evidence for the connection between its metabolic actions and suppression of breast cancer.

CircFBXW8 Acts an Oncogenic Role in the Malignant Progression of Non-Small Cell Lung Carcinoma by miR-370-3p-Dependent Regulation of TRIM44

[Biochemical Genetics] The authors investigated the role of circular RNA F-box and WD repeat domain containing 8 (circFBXW8) in NSCLC progression and the underlying mechanism.

Knockdown of OLR1 Weakens Glycolytic Metabolism to Repress Colon Cancer Cell Proliferation and Chemoresistance by Downregulating SULT2B1 via C-MYC

[Cell Death & Disease] This research was designed to explore the mechanism underlying the OLR1/c-MYC/SULT2B1 axis in the regulation of glycolytic metabolism, to affect colon cancer cell proliferation and chemoresistance.

Transglutaminase 2 Mediates UVB-Induced Matrix Metalloproteinase-1 Expression by Inhibiting Nuclear p65 Degradation in Dermal Fibroblasts

[Experimental Dermatology] In the skin, UV-irradiation increases expression of matrix metalloproteinases (MMPs) that causes dysregulation of extracellular matrix homeostasis in dermis, leading to acceleration of skin aging. Researchers reported the role of transglutaminase 2 in mediating the UVB-induced expression of MMP-1.

Combination Therapy with Novel Androgen Receptor Antagonists and Statin for Castration-Resistant Prostate Cancer

[Prostate] The authors investigated a combination therapy of novel androgen receptor (AR) antagonists and statin, simvastatin, for CRPC and found that a combination of novel AR antagonists and simvastatin could potentially affect CRPC growth through both androgen-dependent and androgen-independent mechanisms.

Popular