Wnt/β-catenin

[International Journal of Biological Macromolecules] Researchers identified a high expression of miRNA-181a-5p in the low-passage exosomes derived from dermal papilla cell (DPC-Exos), revealing the transportation patterns of the DPC-Exos-derived miRNA-181a-5p entering the hair follicle stem cell.

[Cell Reports] Researchers showed that β-catenin stabilization, when targeted to either the mammary luminal or basal epithelial lineage, led to cellular rearrangements that precipitates the formation of hyperplastic lesions that underqwnt squamous transdifferentiation.

[Oncogene] Researchers demonstrated a novel mechanism whereby Wnt/β-catenin signaling pathway was regulated by different kinases in response to metabolic requirement of CSCs, and suggest that SIK2 inhibition may potentially be a strategy for eliminating breast CSCs.

[Stem Cell Reviews and Reports] Quiescent satellite cells were isolated by fluorescence-activated cell sorting, and cell cycle entry was assessed by EdU incorporation.

[Nature Communications] Researchers showed that the endothelial Unc5B receptor controlled blood-brain barrier integrity by maintaining Wnt/β-catenin signaling.

[Biochimica Et Biophysica Acta-Molecular Cell Research] Scientists showed that ANO1 channel protein was upregulated in human colorectal cancer tissue samples and its upregulation was correlated with the TNM staging, histological type, pathological differentiation and poor prognosis.