T-Type Calcium Channel Antagonist, TTA-A2 Exhibits Anti-Cancer Properties in 3D Spheroids of A549, a Lung Adenocarcinoma Cell Line

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Scientists studied TTA-A2 and paclitaxel in lung adenocarcinoma cell line- A549, cancer cells and human embryonic kidney cell line- HEK 293, control cell, in their monolayer and spheroids forms for viability, proliferation, morphology change, migration, and invasion-after 48–96 hours of treatment.
[Life Sciences]
Kumari, N., Bharagava, A., & Rath, S. N. (2020). T-type calcium channel antagonist, TTA-A2 exhibits anti-cancer properties in 3D spheroids of A549, a lung adenocarcinoma cell line. Life Sciences, 118291. https://doi.org/10.1016/j.lfs.2020.118291 Cite
Abstract