Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell NewsScientists evaluate the efficacy and safety of IL-23 inhibitors in the treatment of plaque psoriasis and psoriatic arthritis.
[American Journal of Clinical Dermatology]
6807162 {6807162:VAUQXCRI} apa 50 1 157173 https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3A%22zotpress-d9946f13253a149a2d83fe167b234831%22%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22VAUQXCRI%22%2C%22library%22%3A%7B%22id%22%3A6807162%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Yang%20et%20al.%22%2C%22parsedDate%22%3A%222020-12-10%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EYang%2C%20K.%2C%20Oak%2C%20A.%20S.%20W.%2C%20%26amp%3B%20Elewski%2C%20B.%20E.%20%282020%29.%20Use%20of%20IL-23%20Inhibitors%20for%20the%20Treatment%20of%20Plaque%20Psoriasis%20and%20Psoriatic%20Arthritis%3A%20A%20Comprehensive%20Review.%20%3Ci%3EAmerican%20Journal%20of%20Clinical%20Dermatology%3C%5C%2Fi%3E.%20%3Ca%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs40257-020-00578-0%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs40257-020-00578-0%3C%5C%2Fa%3E%20%3Ca%20title%3D%27Cite%20in%20RIS%20Format%27%20class%3D%27zp-CiteRIS%27%20href%3D%27https%3A%5C%2F%5C%2Fwww.stemcellsciencenews.com%5C%2Fwp-content%5C%2Fplugins%5C%2Fzotpress%5C%2Flib%5C%2Frequest%5C%2Frequest.cite.php%3Fapi_user_id%3D6807162%26amp%3Bitem_key%3DVAUQXCRI%27%3ECite%3C%5C%2Fa%3E%20%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Use%20of%20IL-23%20Inhibitors%20for%20the%20Treatment%20of%20Plaque%20Psoriasis%20and%20Psoriatic%20Arthritis%3A%20A%20Comprehensive%20Review%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kevin%22%2C%22lastName%22%3A%22Yang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Allen%20S.%20W.%22%2C%22lastName%22%3A%22Oak%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Boni%20E.%22%2C%22lastName%22%3A%22Elewski%22%7D%5D%2C%22abstractNote%22%3A%22Psoriasis%20is%20a%20common%20inflammatory%20skin%20disease%20with%20multiple%20comorbidities%2C%20including%20psoriatic%20arthritis%20and%20coronary%20artery%20disease%2C%20that%20can%20severely%20impact%20an%20individual%5Cu2019s%20quality%20of%20life%20and%20daily%20functioning.%20In%20recent%20years%2C%20enhanced%20understanding%20of%20the%20pathogenesis%20of%20psoriasis%2C%20especially%20the%20role%20of%20T%20helper%2017%20cells%2C%20has%20resulted%20in%20the%20development%20of%20new%20classes%20of%20biologic%20drugs%20targeting%20modulators%20along%20its%20disease%20pathway.%20Among%20these%2C%20inhibitors%20of%20interleukin-23%20%28e.g.%2C%20ustekinumab%2C%20guselkumab%2C%20tildrakizumab%2C%20and%20risankizumab%29%20have%20emerged%20as%20safe%20and%20effective%20options%20for%20the%20treatment%20of%20moderate-to-severe%20plaque%20psoriasis%3B%20ustekinumab%20and%20guselkumab%20have%20additionally%20been%20approved%20to%20treat%20psoriatic%20arthritis.%20Selective%20interleukin-23%20inhibitors%20require%20less%20frequent%20dosing%20than%20interleukin-17%20inhibitors%20and%20may%20possess%20a%20more%20favorable%20risk%20profile%20without%20an%20increased%20risk%20of%20candidiasis%20or%20inflammatory%20bowel%20disease.%20Overall%2C%20these%20highly%20effective%20medications%20are%20contributing%20to%20a%20rising%20standard%20for%20psoriasis%20outcomes%20through%20resolution%20of%20skin%20lesions%20and%20joint%20manifestations%20and%20improvement%20of%20patient%20quality%20of%20life.%22%2C%22date%22%3A%222020-12-10%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1007%5C%2Fs40257-020-00578-0%22%2C%22ISSN%22%3A%221179-1888%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs40257-020-00578-0%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222020-12-11T22%3A01%3A49Z%22%7D%7D%5D%7D
Yang, K., Oak, A. S. W., & Elewski, B. E. (2020). Use of IL-23 Inhibitors for the Treatment of Plaque Psoriasis and Psoriatic Arthritis: A Comprehensive Review. American Journal of Clinical Dermatology. https://doi.org/10.1007/s40257-020-00578-0 Cite
