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Pulmonary Cell NewsCoablation of polycomb repressive complex 1 (PRC1) and PRC2 in embryonic epidermal progenitors resulted in severe defects in epidermal stratification, a phenotype not observed in the single PRC1-null or PRC2-null epidermis.
[Genes & Development]
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Cohen, I., Bar, C., Liu, H., Valdes, V. J., Zhao, D., Galbo, P. M., Silva, J. M., Koseki, H., Zheng, D., & Ezhkova, E. (2021). Polycomb complexes redundantly maintain epidermal stem cell identity during development. Genes & Development. https://doi.org/10.1101/gad.345363.120 Cite
