The authors showed that ubiquitin-specific protease 34 (USP34) plays a pivotal role in root formation. Deletion of Usp34 in dental mesenchymal cells led to short root anomaly, characterized by truncated roots and thin root dentin.
[International Journal of Oral Science]
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Jiang, S., Sheng, R., Qi, X., Wang, J., Guo, Y., & Yuan, Q. (2021). USP34 regulates tooth root morphogenesis by stabilizing NFIC. International Journal of Oral Science, 13(1), 1–8. https://doi.org/10.1038/s41368-021-00114-8 Cite