Investigators describe the antitumoral potential of selective cyclin-dependent kinase inhibitors on low-passage glioblastoma multiforme 2D- and 3D models, cultured as neurospheres or glioma stem-like cells.
[Cell Death Discovery]
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Riess, C., Koczan, D., Schneider, B., Linke, C., del Moral, K., Classen, C. F., & Maletzki, C. (2021). Cyclin-dependent kinase inhibitors exert distinct effects on patient-derived 2D and 3D glioblastoma cell culture models. Cell Death Discovery, 7(1), 1–15. https://doi.org/10.1038/s41420-021-00423-1 Cite