Investigators explored the novel mechanisms by which exosome-contained circRNAs promoted tumor development and metastasis in TNBC.
[Cell Death & Disease]
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Yang, S., Wang, D., Zhong, S., Chen, W., Wang, F., Zhang, J., Xu, W., Xu, D., Zhang, Q., Li, J., Zhang, H., Hou, J., Mao, L., & Tang, J. (2021). Tumor-derived exosomal circPSMA1 facilitates the tumorigenesis, metastasis, and migration in triple-negative breast cancer (TNBC) through miR-637/Akt1/β-catenin (cyclin D1) axis. Cell Death & Disease, 12(5), 1–20. https://doi.org/10.1038/s41419-021-03680-1 Cite