Investigators explored thyroid hormone receptor interactor 12’s role in the inhibition of epithelial-mesenchymal transition and implied a potential suppressive role in breast cancer metastasis.
[Cell Death Discovery]
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Lee, K. K., Rajagopalan, D., Bhatia, S. S., Tirado-Magallanes, R., Chng, W. J., & Jha, S. (2021). The oncogenic E3 ligase TRIP12 suppresses epithelial–mesenchymal transition (EMT) and mesenchymal traits through ZEB1/2. Cell Death Discovery, 7(1), 1–15. https://doi.org/10.1038/s41420-021-00479-z Cite