The authors showed that the loss of cell surface expression of Na/K‐ATPase α1 induced epithelial–mesenchymal transition and promoted metastatic potential and tumor growth of prostate cancer by decreasing the expression of E‐cadherin and increasing c‐Myc expression via the activation of Src/FAK pathways.
[Prostate]
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Banerjee, M., Li, Z., Gao, Y., Lai, F., Huang, M., Zhang, Z., Cai, L., Sanabria, J., Gao, T., Xie, Z., & Pierre, S. V. (n.d.). Inverse agonism at the Na/K-ATPase receptor reverses EMT in prostate cancer cells. The Prostate, n/a(n/a). https://doi.org/https://doi.org/10.1002/pros.24144 Cite