Live-Cell Imaging of Glucose-Induced Metabolic Coupling of β and α Cell Metabolism in Health and Type 2 Diabetes

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Researchers used phasor – Fluorescence Lifetime Imaging Microscopy to monitor oxidative phosphorylation and glycolysis in living islet cells before and after glucose stimulation.
[Communications Biology]
Wang, Z., Gurlo, T., Matveyenko, A. V., Elashoff, D., Wang, P., Rosenberger, M., Junge, J. A., Stevens, R. C., White, K. L., Fraser, S. E., & Butler, P. C. (2021). Live-cell imaging of glucose-induced metabolic coupling of β and α cell metabolism in health and type 2 diabetes. Communications Biology, 4(1), 1–11. https://doi.org/10.1038/s42003-021-02113-1 Cite
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