Researchers profiled the host immunotranscriptome response in humans before, during, and after infection with a partially attenuated rDEN2Δ30 challenge virus.
[Nature Communications]
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Hanley, J. P., Tu, H. A., Dragon, J. A., Dickson, D. M., Rio-Guerra, R. del, Tighe, S. W., Eckstrom, K. M., Selig, N., Scarpino, S. V., Whitehead, S. S., Durbin, A. P., Pierce, K. K., Kirkpatrick, B. D., Rizzo, D. M., Frietze, S., & Diehl, S. A. (2021). Immunotranscriptomic profiling the acute and clearance phases of a human challenge dengue virus serotype 2 infection model. Nature Communications, 12(1), 3054. https://doi.org/10.1038/s41467-021-22930-6 Cite