3D Cell Culture Using a Clinostat Reproduces Microgravity-Induced Skin Changes

By
Justin.choi
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Investigators showed that under time-averaged simulated microgravity, the thickness of the endothelial cell arrangement increased by up to 59.75%, indicating skin irritation due to vasodilation, and that the diameter of keratinocytes and fibroblast co-cultured spheroids decreased by 6.66%, representing skin thinning.
[npj Microgravity]
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Choi, D. H., Jeon, B., Lim, M. H., Lee, D. H., Ye, S.-K., Jeong, S.-Y., & Kim, S. (2021). 3D cell culture using a clinostat reproduces microgravity-induced skin changes. Npj Microgravity, 7(1), 1–7. https://doi.org/10.1038/s41526-021-00148-6 Cite
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