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Pulmonary Cell NewsResearchers showed that active mechanical forces increase growth and lead to enhanced patterning in an organoid model of the neural tube derived from single human pluripotent stem cells (hPSC).
[Nature Communications]
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Abdel Fattah, A. R., Daza, B., Rustandi, G., Berrocal-Rubio, M. Á., Gorissen, B., Poovathingal, S., Davie, K., Barrasa-Fano, J., Cóndor, M., Cao, X., Rosenzweig, D. H., Lei, Y., Finnell, R., Verfaillie, C., Sampaolesi, M., Dedecker, P., Van Oosterwyck, H., Aerts, S., & Ranga, A. (2021). Actuation enhances patterning in human neural tube organoids. Nature Communications, 12(1), 3192. https://doi.org/10.1038/s41467-021-22952-0 Cite
