ctDNA Guiding Adjuvant Immunotherapy in Urothelial Carcinoma

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Scientists evaluated outcomes in 581 patients who had undergone surgery and were evaluable for ctDNA from a randomized phase III trial of adjuvant atezolizumab versus observation in operable urothelial cancer.
[Nature]
Powles, T., Assaf, Z. J., Davarpanah, N., Banchereau, R., Szabados, B. E., Yuen, K. C., Grivas, P., Hussain, M., Oudard, S., Gschwend, J. E., Albers, P., Castellano, D., Nishiyama, H., Daneshmand, S., Sharma, S., Zimmermann, B. G., Sethi, H., Aleshin, A., Perdicchio, M., … Mariathasan, S. (2021). ctDNA guiding adjuvant immunotherapy in urothelial carcinoma. Nature, 1–6. https://doi.org/10.1038/s41586-021-03642-9 Cite
Abstract