Reduced Neutralization of SARS-CoV-2 B.1.617 by Vaccine and Convalescent Serum

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Researchers studied the ability of monoclonal antibodies, convalescent and vaccine sera to neutralize B.1.617.1 and B.1.617.2 and complement this with structural analyses of Fab/RBD complexes and map the antigenic space of current variants.
[Cell]
Liu, C., Ginn, H. M., Dejnirattisai, W., Supasa, P., Wang, B., Tuekprakhon, A., Nutalai, R., Zhou, D., Mentzer, A. J., Zhao, Y., Duyvesteyn, H. M. E., López-Camacho, C., Slon-Campos, J., Walter, T. S., Skelly, D., Johnson, S. A., Ritter, T. G., Mason, C., Clemens, S. A. C., … Screaton, G. R. (2021). Reduced neutralization of SARS-CoV-2 B.1.617 by vaccine and convalescent serum. Cell, 0(0). https://doi.org/10.1016/j.cell.2021.06.020 Cite
Abstract