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Pulmonary Cell NewsThe authors aimed at dissecting the cellular and molecular mechanisms driving blood flow-dependent endothelial remodeling. Transcriptomic analysis of endothelial cells revealed that blood flow enhanced VEGFR signaling.
[Scientific Reports]
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Follain, G., Osmani, N., Gensbittel, V., Asokan, N., Larnicol, A., Mercier, L., Garcia-Leon, M. J., Busnelli, I., Pichot, A., Paul, N., Carapito, R., Bahram, S., Lefebvre, O., & Goetz, J. G. (2021). Impairing flow-mediated endothelial remodeling reduces extravasation of tumor cells. Scientific Reports, 11(1), 13144. https://doi.org/10.1038/s41598-021-92515-2 Cite
