Pentraxin 3 Is a Stromally-Derived Biomarker for Detection of Pancreatic Ductal Adenocarcinoma

In vitro and ex vivo analyses of pentraxin 3, in human PDAC samples, pancreatic stellate cells (PSCs), cell lines and transgenic mouse model for PDAC, suggested that pentraxin 3 originated from stromal cells, mainly PSCs.