Extracellular Domain Shedding of the ALK Receptor Mediates Neuroblastoma Cell Migration

By
Justin.choi
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0
11
Investigators mapped the cleavage site to Asn654-Leu655 and demonstrated that cleavage inhibition of wild-type anaplastic lymphoma kinase significantly impeded neuroblastoma cell migration with subsequent prolongation of survival in mouse models.
[Cell Reports]

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