Ileal Derived Organoids from Crohn’s Disease Patients Show Unique Transcriptomic and Secretomic Signatures

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Scientists used patient derived organoids to study the epithelial-specific transcriptional and secretome signatures of the ileum during Crohn’s disease with varying phenotypes to screen for disease profiles and potential druggable targets.
[Cellular and Molecular Gastroenterology and Hepatology]
AbstractFull Article