Human Adipose-Derived Mesenchymal Stromal Cells From Face and Abdomen Undergo Replicative Senescence and Loss of Genetic Integrity After Long-term Culture

The authors evaluated long-term culture of human facial adipose-derived MSCs (fASCs) and abdominal ASCs and showed that both met the criteria for MSC characterization but presented differences in their immunophenotypic profile, and differentiation and clonogenic potentials.