Induction of Sestrin2 by Pterostilbene Suppresses Ethanol-Triggered Hepatocyte Senescence by Degrading CCN1 via p62-Dependent Selective Autophagy

Pterostilbene is a natural compound with hepatoprotective potential; however, its implication for alcoholic liver disease was not understood. Scientists investigated the therapeutic effect of pterostilbene on alcoholic liver disease and elucidate the potential mechanism.