Loss of the Ciliary Protein Chibby1 in Mice Leads to Exocrine Pancreatic Degeneration and Pancreatitis

Scientists reported that Chibby(Cby)1-knockout (KO) mice developed severe exocrine pancreatic atrophy with dilated ducts during early postnatal development. A significant reduction in the number and length of cilia was observed in Cby1-KO pancreta.