Human Adipose-Derived Mesenchymal Stromal Cells Exhibit High HLA-DR Levels and Altered Cellular Characteristics under a Xeno-Free and Serum-Free Condition

Scientists cultured adipose-derived MSCs from seven donors in PowerStem MSC1 media and StemMACS MSC Expansion Media and examined their growth and colony-forming ability, surface marker expression, differentiation, cell cycle and senescence, as well as genetic stability of two passages representing an early and late passage for therapeutic MSCs.