Silencing of Nesprin-2 Inhibits the Differentiation of Myofibroblasts from Fibroblasts Induced by Mechanical Stretch

Investigators constructed a cell model of hypertrophic scar (HTs) and explored the role of Nesprin-2 in this process. Myofibroblasts and fibroblasts were isolated from HTs and healthy skin tissues of the same patient.