Crosstalk Between RPE Cells and Choroidal Endothelial Cells via the ANXA1/FPR2/SHP2/NLRP3 Inflammasome/Pyroptosis Axis Promotes Choroidal Neovascularization

The authors investigated the effect of crosstalk between retinal pigment epithelial (RPE) cells and choroidal endothelial cells via the ANXA1/FPR2/NLRP3 inflammasome/pyroptosis axis on the development of choroidal neovascularization in vitro and in vivo.