PARK7 Promotes Repair in Early Steroid-Induced Osteonecrosis of the Femoral Head by Enhancing Resistance to Stress-Induced Apoptosis in Bone Marrow Mesenchymal Stem Cells via Regulation of the Nrf2 Signaling Pathway

Researchers investigated the mechanism driving a PARK7-mediated resistance to apoptosis in bone marrow MSCs and indicated that PARK7 promoted the disintegration of nuclear factor–like 2 (Nrf2)/Kelch-like echinacoside–associated protein 1 complex.