Single-Cell Profiling of Proteins and Chromatin Accessibility Using PHAGE-ATAC

Researchers developed PHAGE-Assay for Transposase-Accessible Chromatin (ATAC), a massively parallel droplet-based method that used phage displaying, engineered, camelid single-domain antibodies for simultaneous single-cell measurements of protein levels and chromatin accessibility profiles, and mitochondrial DNA-based clonal tracing.