PIM1 Phosphorylation of the Androgen Receptor and 14-3-3 ζ Regulates Gene Transcription in Prostate Cancer

The authors showed that PIM1, a serine/threonine kinase over-expressed in prostate cancer, phosphorylation of androgen receptor (AR) and 14-3-3 ζ extensively occupied the same sites on chromatin in an AR-dependent manner.