AXL Receptor Is Required for Zika Virus Strain MR-766 Infection in Human Glioblastoma Cell Lines

The receptor tyrosine kinase AXL has been identified as an entry receptor for Zika virus (ZIKV) in a cell type-specific manner. Interestingly, AXL was frequently overexpressed in glioblastoma (GBM) patients. The authors demonstrated that ZIKV entry into GBM cells in vitro was mediated by the AXL receptor.