Chemically Defined Stem Cell Microniche Engineering by Microfluidics Compatible with iPSCs’ Growth in 3D Culture

Researchers reported the development of a chemically defined, artificial 3D microniche for iPSCs’ growth and reliable expansion, constructed with degradable polyethyleneglycol-co-polycaprolactone and RGDfk-functionalized dendritic polyglycerol precursors according to bioorthogonal strain-promoted azide-alkyne cycloaddition by droplet-based microfluidics.