NewslettersESC & iPSC NewsUncategorizedSPEN Is Required for Xist Upregulation during Initiation of X Chromosome InactivationBy Justin.choi - December 1, 202104The authors showed that SPEN played an important role in initiation of X chromosome inactivation. Spen null female mouse ESCs were defective in Xist upregulation upon differentiation.[Nature Communications] 7992332 {7992332:CCCCCCCC} apa 50 1 169544 https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/Full Article