Targeting alpha2,3-Sialylated Glycan in Glioma Stem-Like Cells by Maackia amurensis Lectin-II: A Promising Strategy for Glioma Treatment

Scientists established a new glioma stem-like cell, named U373-GSC, from the U373 glioma cell line. The cells exhibited stemness properties, e.g., expression of stem cell markers, self-renewal activity, multi-lineage differentiating abilities, and drug resistance.