PNPLA3 Downregulation Exacerbates the Fibrotic Response in Human Hepatic Stellate Cells

By
Justin.choi
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0
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Scientists characterized hepatic stellate cells obtained from patients carrying the wild type and the heterozygous or homozygous PNPLA3 I148M and investigated the effect of genotype and PNPLA3 downregulation on baseline and TGF-β-stimulated fibrotic gene expression.
[PLoS One]
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