KDM6B Promotes Activation of the Oncogenic CDK4/6-pRB-E2F Pathway by Maintaining Enhancer Activity in MYCN-Amplified Neuroblastoma

0
39
The authors indicated that KDM6B promoted an oncogenic CDK4/6-pRB-E2F pathway in neuroblastoma cells via H3K27me3-dependent enhancer-promoter interactions.
[Nature Communications]
Full Article