Mechanical Force Promotes Dimethylarginine Dimethylaminohydrolase 1-Mediated Hydrolysis of the Metabolite Asymmetric Dimethylarginine to Enhance Bone Formation

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Investigators reported that mechanical force regulated the production of the metabolite asymmetric dimethylarginine via regulating the hydrolytic enzyme dimethylarginine dimethylaminohydrolase 1 expression in osteoblasts.
[Nature Communications]
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