Androgen Receptor-Mediated Paracrine Signaling Induces Regression of Blood Vessels in the Dermal Papilla in Androgenetic Alopecia

Scientists showed that androgen receptor-mediated paracrine signaling, mainly TGF-β signaling, from dermal papilla (DP) cells induced apoptosis of microvascular endothelial cells in the DP of balding scalp of androgenetic alopecia.