APLNR Regulates IFN-γ Signaling via β-Arrestin 1 Mediated JAK-STAT1 Pathway in Melanoma Cells

Researchers showed that activation of apelin receptor (APLNR) upregulated IFN-γ signaling in melanoma cells through APLNR mediated β-arrestin 1 but not β-arrestin 2 recruitment.