Aberrant Upregulation of the Glycolytic Enzyme PFKFB3 in CLN7 Neuronal Ceroid Lipofuscinosis

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Aberrant upregulation of the glycolytic enzyme PFKFB3 in neurons may contribute to CLN7 pathogenesis and targeting PFKFB3 could alleviate this and other lysosomal storage diseases.
[Nature Communications]
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