M6A Demethylase FTO-Mediated Downregulation of DACT1 mRNA Stability Promotes Wnt Signaling to Facilitate Osteosarcoma Progression

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Functional screening showed that the m6A demethylase FTO could be a candidate therapeutic target for osteosarcoma (OS). FTO promoted the growth and metastasis of OS in vitro and in vivo.
[Oncogene]
Abstract