Loss of Glucose 6-Phosphate Dehydrogenase Function Increases Oxidative Stress and Glutaminolysis in Metastasizing Melanoma Cells

By
Justin.choi
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Glucose 6-phosphate dehydrogenase (G6PD) mutant melanomas had significantly decreased G6PD enzymatic activity and depletion of intermediates in the oxidative pentose phosphate pathway.
[Proceedings of the National Academy of Sciences of the United States of America]

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