Hsa_circ_0134111 Promotes Intervertebral Disc Degeneration via Sponging miR-578

Investigators showed that circ_0134111 level was overexpressed in intervertebral disc degeneration (IDD) tissue samples as compared to control tissues. The upregulation of circ_0134111 was more drastic in the moderate and severe IDD cases than in those with mild IDD.