Silencing of Nudix Type 5 Represses Proliferation and Invasion and Enhances Chemosensitivity of Gastric Carcinoma Cells by Affecting the AKT/GSK-3β/β-Catenin Pathway

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A series of cellular functional assays demonstrated that gastric carcinoma cells with silenced NUDT5 exhibited decreased proliferative and invasive ability, increased cell cycle arrest at the G0/G1 phase, and enhanced chemosensitivity.
[Toxicology and Applied Pharmacology]

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Abstract