The Vesicular Transporter STX11 Governs ATGL-Mediated Hepatic Lipolysis and Lipophagy

Scientists demonstrated that syntaxin11 (STX11), a member of the SNARE family, generally expressed in immune cells, mediated lipid metabolism by binding to adipose-triglyceride-lipase (ATGL) and inhibiting lipid droplet degradation and lipid autophagy in hepatocytes.