Exosomal CagA from Helicobacter pylori Aggravates Intestinal Epithelium Barrier Dysfunction in Chronic Colitis by Facilitating Claudin-2 Expression

Chronic colitis models of CagA+ H. pylori-colonized mice treated with 2% Dextran sulphate sodium were established to assess the disease activity and pertinent expression of tight junction proteins closely related to mucosal integrity.