The Role of Clonal Hematopoiesis as Driver of Therapy-Related Myeloid Neoplasms after Autologous Stem Cell Transplantation

Scientists evaluated the mutational profile of 19 lymphoma/myeloma patients, at both pre-autologous stem cell transplantation (pre-ASCT) and therapy-related myeloid neoplasm (t-MN) diagnosis, using a targeted NGS approach; 26 non-developing t-MN control patients were also studied pre-ASCT.